9QB0

Protein kinase CK2 catalytic subunit alpha' (CSNK2A2 gene product) in complex with F2X-Entry screen fragment H07

9QB0 の概要

• エントリーDOI: 10.2210/pdb9qb0/pdb
• 分子名称: Casein kinase II subunit alpha', ~{N}-(4-hydroxyphenyl)-2-pyrazol-1-yl-ethanamide, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: ck2, fragment-based screening, protein kinase, protein kinase ck2, casein kinase ii, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43685.21

構造登録者

Werner, C.,Harasimowicz, H.,Barthel, T.,Weiss, M.S.,Niefind, K. (登録日: 2025-02-28, 公開日: 2026-01-14)

• 主引用文献: Werner, C.,Barthel, T.,Harasimowicz, H.,Marminon, C.,Weiss, M.S.,Borgne, M.L.,Niefind, K.; Crystallographic Fragment Screening with CK2 alpha', an Isoform of Human Protein Kinase CK2 Catalytic Subunit, and Its Use to Obtain a CK2 alpha'/Heparin Complex Structure; Kinases Phosphatases, 4:1-, 2026; DOI: 10.3390/kinasesphosphatases4010001

実験手法

X-RAY DIFFRACTION (1.01 Å)