9PH4

Cryo-EM structure of COP9 signalosome in complex with CSN5i-1a

This is a non-PDB format compatible entry.

Summary for 9PH4

• Entry DOI: 10.2210/pdb9ph4/pdb
• EMDB information: 71639
• Descriptor: COP9 signalosome complex subunit 1, 6-[(4R,5S,6S)-6-hydroxy-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl][1,1'-biphenyl]-3-carbonitrile, COP9 signalosome complex subunit 2, ... (10 entities in total)
• Functional Keywords: cop9, cop9 signalosome, signalosome, nedd8, csn5i-1a, deneddylation, csn5, metalloprotease, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 328640.18

Authors

Shi, H.,Zheng, N. (deposition date: 2025-07-08, release date: 2025-12-03)

• Primary citation: Shi, H.,Zheng, N.; Cryo-EM structure of COP9 signalosome in complex with CSN5i-1a; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)