9ORH

MicroED structure of the CTX-M-14 beta-lactamase-avibactam complex from inhibitor cocktail-soaked crystals

Summary for 9ORH

• Entry DOI: 10.2210/pdb9orh/pdb
• Related: 9ORB 9ORG
• Descriptor: Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total)
• Functional Keywords: enzyme, beta-lactamase, microed, inhibitor, complex, cocktail, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 56279.35

Authors

Vlahakis, N.,Rodriguez, J.A.,Jacobs, L.M.C.,Chen, Y. (deposition date: 2025-05-22, release date: 2025-06-18)

• Primary citation: Vlahakis, N.W.,Flowers, C.W.,Liu, M.,Agdanowski, M.,Johnson, S.,Summers, J.A.,Jacobs, L.M.C.,Keyser, C.,Russell, P.,Rose, S.,Orlans, J.,Adhami, N.,Chen, Y.,Sawaya, M.R.,Basu, S.,De Sanctis, D.,Chen, Y.,Wakatsuki, S.,Nelson, H.M.,Loo, J.A.,Tang, Y.,Rodriguez, J.A.; Combining MicroED and native mass spectrometry for structural discovery of enzyme-small molecules complexes; To Be Published,

Experimental method

ELECTRON CRYSTALLOGRAPHY (2 Å)