9OK9
Crystal structure of an MKP5 allosteric loop mutant, P447V, in complex with an allosteric inhibitor
Summary for 9OK9
| Entry DOI | 10.2210/pdb9ok9/pdb |
| Descriptor | Dual specificity protein phosphatase 10, 3,3-dimethyl-1-{[9-(methylsulfanyl)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl]sulfanyl}butan-2-one (2 entities in total) |
| Functional Keywords | allosteric site, hydrolase-inhibitor complex, hydrolase/inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 6 |
| Total formula weight | 105205.50 |
| Authors | |
| Primary citation | Manjula, R.,Bennett, A.M.,Lolis, E. Crystal structure of an MKP5 allosteric loop mutant, S446G, in complex with an allosteric inhibitor To Be Published, |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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