9NPJ

Structural studies of reaction hijacking inhibition of a malaria parasite aspartyl-tRNA synthetase.

This is a non-PDB format compatible entry.

Summary for 9NPJ

• Entry DOI: 10.2210/pdb9npj/pdb
• Descriptor: aspartate--tRNA ligase, 9-(5-O-{[(1R,2R)-2-amino-3-carboxy-1-hydroxypropyl]sulfamoyl}-beta-D-lyxofuranosyl)-2-chloro-9H-purin-6-amine, GLYCEROL, ... (4 entities in total)
• Functional Keywords: t-rna synthetase, malaria, inhibitor, ligase
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum)
• Total number of polymer chains: 2
• Total formula weight: 125437.55

Authors

Khandokar, Y.,Ketprasit, K.,Tai, C.W.,Xie, S.,Tilley, L.,Griffin, M.D.W.,Panjikar, S. (deposition date: 2025-03-11, release date: 2025-06-04)

• Primary citation: Khandokar, Y.,Ketprasit, K.,Xie, S.,Tilley, L.,Griffin, M.D.W.,Panjikar, S.; Structural studies of reaction hijacking inhibition of a malaria parasite aspartyl-tRNA synthetase.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.36 Å)