9N8Q

Crystal structure of Trastuzumab Fab with P151A

Summary for 9N8Q

• Entry DOI: 10.2210/pdb9n8q/pdb
• Related: 9MVX
• Descriptor: Trastuzumab Fab Heavy chain, Trastuzumab Fab Light chain, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• Functional Keywords: human fab fragment, immune response, immune system, proala, proline-to-alanine, bispecific antibody, bsab, bsigg, cis-peptide, trastuzumab, fab
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 48463.95

Authors

Choi, W.S.,Tilegenova, C.,Are, M.,Zwolak, A.,Shaffer, P.,Sharma, S. (deposition date: 2025-02-09, release date: 2025-10-22)

• Primary citation: Tilegenova, C.,Liu, T.,Zhao, Q.,Are, M.,Zhao, Y.,Choi, W.S.,Bhaumik, A.,Steele, R.,Manieri, N.,Turegun, B.,Shaffer, P.,Ernst, R.,Sharma, S.,Cheung, W.,Zwolak, A.; Folding-Mediated Secretion of Pure Bispecific Antibodies; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)