9N5H

Endogenous Pfs230D1-6 in complex with RUPA-97, LMIV230-01, and 2A2 Fab domains

Summary for 9N5H

• Entry DOI: 10.2210/pdb9n5h/pdb
• EMDB information: 48921
• Descriptor: Gametocyte surface protein P230, 2A2 Heavy Chain, 2A2 Kappa Chain, ... (7 entities in total)
• Functional Keywords: 6-cys, antibody, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 7
• Total formula weight: 505104.87

Authors

Heide, F.,Yoo, R.,Ivanochko, D.,Hailemariam, S.,Bekkering, E.,Julien, J.P. (deposition date: 2025-02-04, release date: 2025-10-15)

• Primary citation: Bekkering, E.T.,Yoo, R.,Hailemariam, S.,Heide, F.,Ivanochko, D.,Jackman, M.,Proellochs, N.I.,Stoter, R.,van Gemert, G.J.,Maeda, A.,Yuguchi, T.,Wanders, O.T.,van Daalen, R.C.,Inklaar, M.R.,Andrade, C.M.,Jansen, P.W.T.C.,Vermeulen, M.,Bousema, T.,Takashima, E.,Rubinstein, J.L.,Kooij, T.W.A.,Jore, M.M.,Julien, J.P.; Structure of endogenous Pfs230:Pfs48/45 in complex with potent malaria transmission-blocking antibodies.; Immunity, 2025

Experimental method

ELECTRON MICROSCOPY (3.6 Å)