9MZ3

Structure of human endothelial nitric oxide synthase heme domain bound 2-(2-amino-6-fluoro-4-methylquinolin-7-yl)-5-(2-aminoethyl)phenol

This is a non-PDB format compatible entry.

Summary for 9MZ3

• Entry DOI: 10.2210/pdb9mz3/pdb
• Descriptor: Nitric oxide synthase, endothelial, ZINC ION, CALCIUM ION, ... (12 entities in total)
• Functional Keywords: nitric oxide synthase inhibitor binding, oxidoreductase-inhibitor complex, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 206016.33

Authors

Li, H.,Poulos, T.L. (deposition date: 2025-01-22, release date: 2025-12-03)

• Primary citation: Ansari, A.,Rathnayake, A.D.,Li, H.,Hardy, C.D.,Poulos, T.L.,Silverman, R.B.; Design and synthesis of 7-aryl-6-fluoro-2-aminoquinolines as potent and highly selective human neuronal nitric oxide synthase inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)