9MWF

Structure of rat neuronal nitric oxide synthase R349A mutant heme domain bound with N-(4-(2-((3-(isoxazole-3-carboximidamido)benzyl)amino)ethyl)phenyl)isoxazole-3-carboximidamide

This is a non-PDB format compatible entry.

Summary for 9MWF

• Entry DOI: 10.2210/pdb9mwf/pdb
• Descriptor: Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (8 entities in total)
• Functional Keywords: nitric oxide synthase inhibitor binding, oxidoreductase
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 1
• Total formula weight: 50290.22

Authors

Li, H.,Poulos, T.L. (deposition date: 2025-01-17, release date: 2025-11-26)

• Primary citation: Awasthi, A.,Li, H.,Hardy, C.D.,Poulos, T.L.,Silverman, T.L.; A step forward for neuronal Nitric Oxide Synthase Inhibitors against Melanoma; To be published,

Experimental method

X-RAY DIFFRACTION (2.07 Å)