9MNM

SPA of purified HIV-1 CA protein in vitro assembled with IP6 (mature morphology). 50 uM LEN was added post assembly.

Summary for 9MNM

• Entry DOI: 10.2210/pdb9mnm/pdb
• Related: 9MNK 9MNL
• EMDB information: 48428 48429 48430
• Descriptor: Capsid protein p24, Lenacapavir, INOSITOL HEXAKISPHOSPHATE (3 entities in total)
• Functional Keywords: hiv, mature, vlp, lenacapavir, virus like particle
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 106746.62

Authors

Ricana, C.L.,Dick, R.A. (deposition date: 2024-12-22, release date: 2026-01-14)

• Primary citation: Ricana, C.L.,Brancato, S.G.,Highland, C.M.,Ekbataniamiri, F.,Ambrus, K.,Rey, J.S.,Faerch, M.,Perilla, J.R.,Dick, R.A.; Structural Analysis of HIV-1 Capsid Disruption by Lenacapavir Using Cryo-EM; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.5 Å)