9M1C

Vitamin D receptor complex with a triphenylpropylsilane derivative

This is a non-PDB format compatible entry.

Summary for 9M1C

• Entry DOI: 10.2210/pdb9m1c/pdb
• Descriptor: Vitamin D3 receptor, Mediator of RNA polymerase II transcription subunit 1, (4~{S})-5-[4-[[4-(2-ethyl-2-oxidanyl-butoxy)-3-methyl-phenyl]-methyl-phenyl-silyl]-2-methyl-phenoxy]-4-oxidanyl-pentanoic acid, ... (4 entities in total)
• Functional Keywords: vitamin d receptor, transcription
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 2
• Total formula weight: 32716.69

Authors

Thilakarathne, N.M.H.N.,Hanazono, Y.,Ito, N.,Kagechika, H.,Fujii, S. (deposition date: 2025-02-25, release date: 2025-06-11)

• Primary citation: Mudiyanselage, H.N.T.N.,Misawa, T.,Ochiai, K.,Demizu, Y.,Hanazono, Y.,Ito, N.,Fujii, S.; Structure-activity relationship and crystallographic analyses of non-secosteroidal vitamin D receptor ligands bearing diphenylsilane core as a hydrophobic pharmacophore; Bioorg.Med.Chem., :118261-, 2025; DOI: 10.1016/j.bmc.2025.118261

Experimental method

X-RAY DIFFRACTION (1.67 Å)