9JWX

NifS soaked with(2R,3R)-3-ethoxycarbonylaziridine-2-carboxylic acid

Summary for 9JWX

• Entry DOI: 10.2210/pdb9jwx/pdb
• Descriptor: Cysteine desulfurase IscS, ISOPROPYL ALCOHOL, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: cysteine desulfurase, biosynthetic protein
• Biological source: Helicobacter pylori 26695
• Total number of polymer chains: 1
• Total formula weight: 44448.90

Authors

Otsuka, H.,Nakamura, R.,Fujishiro, T. (deposition date: 2024-10-11, release date: 2025-07-16)

• Primary citation: Fujishiro, T.,Otsuka, H.,Nakamura, R.,Fujihara, T.; Discovery of an Aziridine-Based Inhibitor That Targets Cysteine Desulfurase Type II SufS via High-Throughput X-ray Crystallography; Acs Med.Chem.Lett., 2025; DOI: 10.1021/acsmedchemlett.5c00168

Experimental method

X-RAY DIFFRACTION (2.8 Å)