9JBQ
Structure of the complex between h1F3 Fab and PcrV fragment
Summary for 9JBQ
Entry DOI | 10.2210/pdb9jbq/pdb |
Descriptor | Heavy chain, light chain, PcrV, ... (4 entities in total) |
Functional Keywords | complex, fab, antimicrobial protein, antimicrobial protein-immune system complex, antimicrobial protein/immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 62646.86 |
Authors | Numata, S.,Hara, T.,Izawa, M.,Okuno, Y.,Sato, Y.,Yamane, S.,Maki, H.,Sato, T.,Yamano, Y. (deposition date: 2024-08-27, release date: 2024-09-11, Last modification date: 2024-10-16) |
Primary citation | Numata, S.,Hara, T.,Izawa, M.,Okuno, Y.,Sato, Y.,Yamane, S.,Maki, H.,Sato, T.,Yamano, Y. Novel humanized anti-PcrV monoclonal antibody COT-143 protects mice from lethal Pseudomonas aeruginosa infection via inhibition of toxin translocation by the type III secretion system. Antimicrob.Agents Chemother., 68:e0069424-e0069424, 2024 Cited by PubMed: 39269189DOI: 10.1128/aac.00694-24 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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