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9JBJ

Cryo-EM structure of the human LYCHOS Y57A/R61A mutant in the expanded state

Summary for 9JBJ
Entry DOI10.2210/pdb9jbj/pdb
Related9JBE
EMDB information61316
DescriptorLysosomal cholesterol signaling protein (1 entity in total)
Functional Keywordspermease-like domain, gpcr-like domain, cholesterol, mtorc1, membrane protein
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight195711.20
Authors
Yu, S.,Liang, L. (deposition date: 2024-08-27, release date: 2025-07-16)
Primary citationYu, S.,Liang, L.
Structural insights into cholesterol sensing by the LYCHOS-mTORC1 pathway
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.73 Å)
Structure validation

239492

数据于2025-07-30公开中

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