9IXB

Structure of tubulin and nitrogen-containing heterocyclic substituted podophyllotoxin derivatives complex

This is a non-PDB format compatible entry.

Summary for 9IXB

• Entry DOI: 10.2210/pdb9ixb/pdb
• Descriptor: Detyrosinated tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, (5~{S},5~{a}~{S},8~{a}~{R},9~{R})-5-(1~{H}-indazol-5-ylamino)-9-(3,4,5-trimethoxyphenyl)-5~{a},6,8~{a},9-tetrahydro-5~{H}-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one, ... (15 entities in total)
• Functional Keywords: tublin, gtp, inhibitor, two binding sites, cell cycle
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 6
• Total formula weight: 258088.75

Authors

Bi, J.,Zhao, W. (deposition date: 2024-07-27, release date: 2025-07-30)

• Primary citation: Bi, J.; Structure of tubulin and nitrogen-containing heterocyclic substituted podophyllotoxin derivatives complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.48 Å)