9IPM

Hemichannel sub-structure of Cx36/GJD2 gap junction intercellular channel (FN conformation) in soybean polar lipid nanodiscs, treated with a 20-fold molar excess of carbenoxolone

9IPM の概要

• エントリーDOI: 10.2210/pdb9ipm/pdb
• EMDBエントリー: 60775 60777
• 分子名称: Gap junction delta-2 protein,Soluble cytochrome b562, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, TETRADECANE (3 entities in total)
• 機能のキーワード: gap junction, connexin36, inhibitor, carbenoxolone, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 255538.08

構造登録者

Jang, H.S. (登録日: 2024-07-11, 公開日: 2026-01-21)

• 主引用文献: Lee, C.W.,Jang, H.S.,Woo, J.S.; Structural insights into the closing mechanism of gap junction intercellular channels by carbenoxolone; To Be Published,

実験手法

ELECTRON MICROSCOPY (3.56 Å)