9HQO

Cryo-EM structure of bovine TMEM206-YFP purified and plunged using MISO (micro-purification)

Summary for 9HQO

• Entry DOI: 10.2210/pdb9hqo/pdb
• EMDB information: 52345
• Descriptor: Proton-activated chloride channel (1 entity in total)
• Functional Keywords: ph-gated chloride channel, membrane protein
• Biological source: Bos taurus (domestic cattle)
• Total number of polymer chains: 3
• Total formula weight: 91127.64

Authors

De Gieter, S.,Eluru, G.,Schenck, S.,Stroobants, A.,Efremov, R.G.,Brunner, J.D. (deposition date: 2024-12-16, release date: 2025-11-05)

• Primary citation: Eluru, G.,De Gieter, S.,Schenck, S.,Stroobants, A.,Shrestha, B.,Erbel, P.,Brunner, J.D.,Efremov, R.G.; MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony; Nat.Methods, 2025; DOI: 10.1038/s41592-025-02894-x

Experimental method

ELECTRON MICROSCOPY (2.97 Å)