9HQN

Cryo-EM structure of bovine TMEM206

Summary for 9HQN

• Entry DOI: 10.2210/pdb9hqn/pdb
• EMDB information: 52344
• Descriptor: Proton-activated chloride channel, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: chloride channel gated by ph that facilitates the entry of chloride ions into cells upon exposure to extracellular acidic ph, membrane protein
• Biological source: Bos taurus (domestic cattle)
• Total number of polymer chains: 3
• Total formula weight: 121206.32

Authors

Brunner, J.D.,Schenck, S.,De Gieter, S. (deposition date: 2024-12-16, release date: 2025-11-05)

• Primary citation: Eluru, G.,De Gieter, S.,Schenck, S.,Stroobants, A.,Shrestha, B.,Erbel, P.,Brunner, J.D.,Efremov, R.G.; MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony; Nat.Methods, 2025; DOI: 10.1038/s41592-025-02894-x

Experimental method

ELECTRON MICROSCOPY (2.86 Å)