9HGJ

HSV-1 Origin Binding Protein in complex with double-stranded DNA recognition sequence OriS and non-hydrolyzable ATP analog

Summary for 9HGJ

• Entry DOI: 10.2210/pdb9hgj/pdb
• EMDB information: 52145
• Descriptor: Replication origin-binding protein, DNA (5'-D(P*TP*AP*TP*TP*GP*GP*GP*AP*CP*GP*AP*AP*GP*TP*GP*CP*GP*AP*AP*CP*GP*CP*TP*T)-3'), DNA (5'-D(P*AP*AP*GP*CP*GP*TP*TP*CP*GP*CP*AP*CP*TP*TP*CP*GP*TP*CP*CP*CP*AP*AP*TP*A)-3'), ... (5 entities in total)
• Functional Keywords: dna, helicase, complex, dna binding protein
• Biological source: Human alphaherpesvirus 1 strain KOS; More
• Total number of polymer chains: 4
• Total formula weight: 240184.82

Authors

Gustavsson, E.,Grunewald, K.,Elias, P.,Hallberg, B.M. (deposition date: 2024-11-19, release date: 2025-10-22)

• Primary citation: Gustavsson, E.,Grunewald, K.,Elias, P.,Hallberg, B.M.; The Herpes simplex Origin Binding Protein: Mechanisms for sequence specific DNA binding and dimerization revealed by Cryo-EM; Nucleic Acids Res., 2025; DOI: 10.1093/nar/gkaf1029

Experimental method

ELECTRON MICROSCOPY (3.53 Å)