9HCI

structure of the double Cys-substituted cross-linked AcrB variant S562C_T837C

Summary for 9HCI

• Entry DOI: 10.2210/pdb9hci/pdb
• Descriptor: Multidrug efflux pump subunit AcrB, nonane, SULFATE ION, ... (12 entities in total)
• Functional Keywords: rnd multidrug efflux pump, antimicrobial resistance, intermediate conformational state, crosslinked structure, transport protein
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 5
• Total formula weight: 389328.32

Authors

Brandstaetter, L.,Mueller, R.T.,Pos, K.M. (deposition date: 2024-11-10, release date: 2025-11-19)

• Primary citation: Boernsen, C.,Mueller, R.T.,Pos, K.M.; Molecular mechanism of transition-state inhibitors of bacterial antibiotic efflux pumps; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)