9GFD

Crystal structure of ASO binding Fab fragment with ASO139

This is a non-PDB format compatible entry.

Summary for 9GFD

• Entry DOI: 10.2210/pdb9gfd/pdb
• Descriptor: Fab fragment heavy chain, Fab Fragment light chain, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: antibody, fab fragment, aso, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 49438.80

Authors

Hsia, H.-E.,Zanini, C.,Simonneau, C.,Fraidling, J.,Kraft, T.,Mayer, K.,Sommer, A.,Indlekofer, A.,Wirth, T.,Benz, J.,Geroges, G.,Langer, M.L.,Gassner, C.,Larraillet, V.,Manso, M.,Ravn, J.,Hofer, K.,Emrich, T.,Niewoehner, J.,Schumacher, F.,Brinkmann, U. (deposition date: 2024-08-09, release date: 2025-08-20)

• Primary citation: Hsia, H.-E.,Zanini, C.,Simonneau, C.,Fraidling, J.,Kraft, T.,Mayer, K.,Sommer, A.,Indlekofer, A.,Wirth, T.,Benz, J.,Geroges, G.,Langer, M.L.,Gassner, C.,Larraillet, V.,Manso, M.,Ravn, J.,Hofer, K.,Emrich, T.,Niewoehner, J.,Schumacher, F.,Brinkmann, U.; Improved Targeted Delivery of Antisense Oligonucleotide Conjugates with the Antibody Mask; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.43 Å)