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9G2D

Cryo-EM structure of the beta3 homomeric GABA(A) receptor in the long-lived resting state (C5) sprayed with PBS

Summary for 9G2D
Entry DOI10.2210/pdb9g2d/pdb
EMDB information50973
DescriptorGamma-aminobutyric acid receptor subunit beta-3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywordsgaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
Biological sourceHomo sapiens (human)
Total number of polymer chains5
Total formula weight236175.65
Authors
Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-07-10, release date: 2025-07-23)
Primary citationMihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in the long-lived resting state (C5) sprayed with PBS
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.7 Å)
Structure validation

239149

数据于2025-07-23公开中

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