9FOF
Structure of heteromeric amyloid filament of TDP-43 and AXNA11 from FTLD-TDP Type C (variant 2)
Summary for 9FOF
Entry DOI | 10.2210/pdb9fof/pdb |
EMDB information | 50621 |
Descriptor | TAR DNA-binding protein 43, Annexin A11 (2 entities in total) |
Functional Keywords | tdp-43, anxa11, amyloid, heteromeric amyloid, ftld-tdp, neurodegeneration, dementia, brain, protein filament, protein fibril |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 60222.11 |
Authors | |
Primary citation | Arseni, D.,Nonaka, T.,Jacobsen, M.H.,Murzin, A.G.,Cracco, L.,Peak-Chew, S.Y.,Garringer, H.J.,Kawakami, I.,Suzuki, H.,Onaya, M.,Saito, Y.,Murayama, S.,Geula, C.,Vidal, R.,Newell, K.L.,Mesulam, M.,Ghetti, B.,Hasegawa, M.,Ryskeldi-Falcon, B. Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C. Biorxiv, 2024 Cited by PubMed: 38979278DOI: 10.1101/2024.06.25.600403 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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