9FG3

Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 bound twice in the long-lived symmetric desensitised state

9FG3 の概要

• エントリーDOI: 10.2210/pdb9fg3/pdb
• EMDBエントリー: 50383
• 分子名称: Gamma-aminobutyric acid receptor subunit alpha-1, (19S,22R,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9E)-octadec-9-enoate, GAMMA-AMINO-BUTANOIC ACID, ... (11 entities in total)
• 機能のキーワード: gaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 266326.43

構造登録者

Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (登録日: 2024-05-23, 公開日: 2025-06-04)

• 主引用文献: Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.; Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 bound twice in the long-lived symmetric desensitised state; To Be Published,

実験手法

ELECTRON MICROSCOPY (3.1 Å)