9FCG

Medicago truncatula 5'-ProFAR isomerase (HISN3) D57N mutant in complex with PrFAR

Summary for 9FCG

Entry DOI	10.2210/pdb9fcg/pdb
Descriptor	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total)
Functional Keywords	complex, product, side-product, bbm ii isomerase, histidine biosynthesis, hisa, isomerase
Biological source	Medicago truncatula (barrel medic)
Total number of polymer chains	1
Total formula weight	31336.76
Authors	Witek, W.,Imiolczyk, B.,Ruszkowski, M. (deposition date: 2024-05-15, release date: 2024-09-04)
Primary citation	Witek, W.,Imiolczyk, B.,Ruszkowski, M. Structural, kinetic, and evolutionary peculiarities of HISN3, a plant 5'-ProFAR isomerase. Plant Physiol Biochem., 215:109065-109065, 2024 Cited by PubMed: 39186852 DOI: 10.1016/j.plaphy.2024.109065 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.54 Å)

Structure validation