9FCD

CysG(N-16) in complex with SAH from Kitasatospora cystarginea

Summary for 9FCD

Entry DOI	10.2210/pdb9fcd/pdb
Descriptor	SAM-dependent methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, CALCIUM ION, ... (8 entities in total)
Functional Keywords	natural product biosynthesis, enzyme mechanism, metal ion interaction, molecular docking, structure function relationships, transferase
Biological source	Kitasatospora cystarginea
Total number of polymer chains	1
Total formula weight	25206.17
Authors	Kuttenlochner, W.,Beller, P.,Kaysser, L.,Groll, M. (deposition date: 2024-05-15, release date: 2024-08-21)
Primary citation	Kuttenlochner, W.,Beller, P.,Kaysser, L.,Groll, M. Deciphering the SAM- and Metal-Dependent Mechanism of O-Methyltransferases in Cystargolide and Belactosin Biosynthesis: A Structure-Activity Relationship Study. J.Biol.Chem., :107646-107646, 2024 Cited by PubMed: 39121999 DOI: 10.1016/j.jbc.2024.107646 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation