9FAT

CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2, Megabody38 and pregnenolone sulfate

9FAT の概要

• エントリーDOI: 10.2210/pdb9fat/pdb
• EMDBエントリー: 50281
• 分子名称: Gamma-aminobutyric acid receptor subunit alpha-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (22 entities in total)
• 機能のキーワード: gaba, neurotransmission, ternary complex, inhibitory synapse, neurosteroid, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 338955.91

構造登録者

Kasaragod, V.B.,Aricescu, A.R. (登録日: 2024-05-10, 公開日: 2025-07-02)

• 主引用文献: Kasaragod, V.B.,Aricescu, A.R.; CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2, Megabody38 and pregnenolone sulfate; To Be Published,

実験手法

ELECTRON MICROSCOPY (3.6 Å)