9FAJ

CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38, in a desensitised state (StateD1)

9FAJ の概要

• エントリーDOI: 10.2210/pdb9faj/pdb
• EMDBエントリー: 50273
• 分子名称: Gamma-aminobutyric acid receptor subunit alpha-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (23 entities in total)
• 機能のキーワード: gaba, neurotransmission, synaptic capture complex, inhibitory synapse, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 404378.75

構造登録者

Kasaragod, V.B.,Aricescu, A.R. (登録日: 2024-05-10, 公開日: 2025-07-02)

• 主引用文献: Kasaragod, V.B.,Aricescu, A.R.; CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38, in a desensitised state (StateD1); To Be Published,

実験手法

ELECTRON MICROSCOPY (2.6 Å)