9F6I
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Post-Insertion state)
Summary for 9F6I
| Entry DOI | 10.2210/pdb9f6i/pdb |
| EMDB information | 50225 |
| Descriptor | DNA polymerase epsilon catalytic subunit A, DNA nascent strand, DNA template strand, ... (6 entities in total) |
| Functional Keywords | dna, polymerase, epsilon, pcna, leading strand, human, replication, replisome, proofreading |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 157951.68 |
| Authors | Roske, J.J.,Yeeles, J.T.P. (deposition date: 2024-05-01, release date: 2024-08-07, Last modification date: 2024-08-21) |
| Primary citation | Roske, J.J.,Yeeles, J.T.P. Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 39112807DOI: 10.1038/s41594-024-01370-y PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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