9F4E

UP1 in complex with Z1152242726

Summary for 9F4E

• Entry DOI: 10.2210/pdb9f4e/pdb
• Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(6-methoxypyridin-3-yl)-N'-thiophen-2-ylurea (3 entities in total)
• Functional Keywords: fragment screening, hnrnp a1, up1, rna/dna binding protein, up1-fragment complex, rna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 22606.40

Authors

Dunnett, L.,Prischi, F. (deposition date: 2024-04-27, release date: 2024-05-08)

• Primary citation: Dunnett, L.,Prischi, F.; Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.57 Å)