9F2I

Crystal structure of SARS-CoV-2 N-protein C-terminal domain in complex with 2-amino-1,3-benzothiazol-6-ol

This is a non-PDB format compatible entry.

Summary for 9F2I

• Entry DOI: 10.2210/pdb9f2i/pdb
• Related: 9F2G 9F2H
• Descriptor: Nucleoprotein, 2-amino-1,3-benzothiazol-6-ol, SULFATE ION, ... (5 entities in total)
• Functional Keywords: ctd, sars-cov-2 nucleocapsid, covid-19, riluzole, benzothiazols, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 8
• Total formula weight: 100989.48

Authors

Marquez-Monino, M.A.,Gonzalez, B.,Perez-Canadillas, J.M. (deposition date: 2024-04-23, release date: 2024-11-13)

• Primary citation: Marquez-Monino, M.A.,Santiveri, C.M.,de Leon, P.,Camero, S.,Campos-Olivas, R.,Jimenez, M.A.,Saiz, M.,Gonzalez, B.,Perez-Canadillas, J.M.; The ALS drug riluzole binds to the C-terminal domain of SARS-CoV-2 nucleocapsid protein and has antiviral activity.; Structure, 2024; DOI: 10.1016/j.str.2024.10.025

Experimental method

X-RAY DIFFRACTION (1.45 Å)