9ETS の概要
| エントリーDOI | 10.2210/pdb9ets/pdb |
| EMDBエントリー | 19960 |
| 分子名称 | DUF4352 domain-containing protein, 6-deoxy-6-sulfo-beta-D-glucopyranose-(1-3)-[alpha-D-mannopyranose-(1-4)][alpha-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
| 機能のキーワード | cell surface appendage, n-glycosylation, protein fibril |
| 由来する生物種 | Sulfolobus acidocaldarius |
| タンパク質・核酸の鎖数 | 37 |
| 化学式量合計 | 614339.98 |
| 構造登録者 | |
| 主引用文献 | Gaines, M.C.,Isupov, M.N.,McLaren, M.,Mollat, C.L.,Haque, R.U.,Stephenson, J.K.,Sivabalasarma, S.,Hanus, C.,Kattnig, D.,Gold, V.A.M.,Albers, S.,Daum, B. Towards a molecular picture of the archaeal cell surface. Nat Commun, 15:10401-10401, 2024 Cited by PubMed Abstract: Archaea produce various protein filaments with specialised functions. While some archaea produce only one type of filament, the archaeal model species Sulfolobus acidocaldarius generates four. These include rotary swimming propellers analogous to bacterial flagella (archaella), pili for twitching motility (Aap), adhesive fibres (threads), and filaments facilitating homologous recombination upon UV stress (UV pili). Here, we use cryo-electron microscopy to describe the structure of the S. acidocaldarius archaellum at 2.0 Å resolution, and update the structures of the thread and the Aap pilus at 2.7 Å and 2.6 Å resolution, respectively. We define features unique to archaella of the order Sulfolobales and compare their structure to those of Aap and threads in the context of the S-layer. We define distinct N-glycan patterns in the three filaments and identify a putative O-glycosylation site in the thread. Finally, we ascertain whether N-glycan truncation leads to structural changes in archaella and Aap. PubMed: 39614099DOI: 10.1038/s41467-024-53986-9 主引用文献が同じPDBエントリー |
| 実験手法 | ELECTRON MICROSCOPY (2.6 Å) |
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