9ET7

CDK2-cyclin A in complex with FragLite 6

Summary for 9ET7

• Entry DOI: 10.2210/pdb9et7/pdb
• Descriptor: Cyclin-dependent kinase 2, Cyclin-A2, 4-bromanyl-1~{H}-pyridin-2-one, ... (4 entities in total)
• Functional Keywords: cyclin-dependent kinase, fraglite, cdk2, cyclin a, fragment, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 130866.47

Authors

Hope, I.,Martin, M.P.,Waring, M.J.,Noble, M.E.M.,Endicott, J.A.,Tatum, N.J. (deposition date: 2024-03-26, release date: 2025-04-09)

• Primary citation: Hope, I.,Martin, M.P.,Waring, M.J.,Noble, M.E.M.,Endicott, J.A.,Tatum, N.J.; Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.312 Å)