9EKH

Cryo-EM structure ONO3030297-bound prostaglandin D2 receptor (DP1)-bRIL-Fab complex

This is a non-PDB format compatible entry.

Summary for 9EKH

• Entry DOI: 10.2210/pdb9ekh/pdb
• EMDB information: 48122
• Descriptor: Prostaglandin D2 receptor,Soluble cytochrome b562, anti-BRIL Fab Heavy Chain, anti-Fab Nanobody, ... (6 entities in total)
• Functional Keywords: gpcr, cryo-em, dp1, inverse agonist, ono3030297, prostaglandin d2 receptor, prostanoid dp receptor, pgd receptor, ptgdr, dp1-bril chimera, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 117495.79

Authors

Davoudinasab, B.,Cherezov, V.,Han, G.W.,Kim, D. (deposition date: 2024-12-02, release date: 2025-09-03)

• Primary citation: Davoudinasab, B.,Han, G.W.,Cherezov, V.; Structural insights into mechanism of activation and deactivation of prostaglandin receptors; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.89 Å)