9EF4

Cryo-EM structure of Drosophila melanogaster insulin receptor (dmIR) bound with two DILP1, symmetric conformation

Summary for 9EF4

• Entry DOI: 10.2210/pdb9ef4/pdb
• EMDB information: 47969
• Descriptor: DILP1 B-chain, DILP1 A-chain, Insulin-like receptor, ... (4 entities in total)
• Functional Keywords: insulin receptor, dilp, structural protein
• Biological source: Drosophila melanogaster (fruit fly); More
• Total number of polymer chains: 6
• Total formula weight: 498455.67

Authors

Bai, X.C. (deposition date: 2024-11-19, release date: 2025-10-01)

• Primary citation: Bai, X.C.; Structural basis of the activation of the Drosophila insulin receptor by three Drosophila insulin-like peptides; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.9 Å)