9EE5

Cryo-EM structure of the ONO2550289-bound prostaglandin D2 receptor (DP1)-bRIL-Fab complex

This is a non-PDB format compatible entry.

Summary for 9EE5

• Entry DOI: 10.2210/pdb9ee5/pdb
• EMDB information: 47950
• Descriptor: anti-BRIL Fab Heavy Chain, anti-Fab Nanobody synthetic construct, anti-BRIL Fab Light Chain, ... (5 entities in total)
• Functional Keywords: gpcr, cryo-em, dp1, inverse agonist, ono2550289, prostaglandin d2 receptor, prostanoid dp receptor, pgd receptor, ptgdr, dp1-bril chimera, membrane protein, membrane protein-immune system complex, membrane protein/immune system
• Biological source: synthetic construct; More
• Total number of polymer chains: 4
• Total formula weight: 117248.55

Authors

Davoudinasab, B.,Cherezov, V.,Han, G.W. (deposition date: 2024-11-18, release date: 2025-09-03)

• Primary citation: Davoudinasab, B.,Han, G.W.,Cherezov, V.; Structural insights into mechanism of activation and deactivation of prostaglandin receptors; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.89 Å)