9EDX

Crystal structure of Yck2 from Candida albicans in complex with inhibitor 2a: 2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine-6-carbonitrile

This is a non-PDB format compatible entry.

Summary for 9EDX

• Entry DOI: 10.2210/pdb9edx/pdb
• Descriptor: non-specific serine/threonine protein kinase, 2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine-6-carbonitrile, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: yck2, kinase, kinase inhibitor, structural genomics, center for structural bioloy of infectious diseases, niaid, national institute of allergy and infectious diseases, transferase, transferase-inhibitor complex, center for structural biology of infectious diseases, csbid, transferase/inhibitor
• Biological source: Candida albicans
• Total number of polymer chains: 1
• Total formula weight: 35782.48

Authors

Stogios, P.J.,Whitesell, L.,Cowen, L.E.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Biology of Infectious Diseases (CSBID) (deposition date: 2024-11-18, release date: 2025-01-08)

• Primary citation: Stogios, P.J.; Crystal structure of Yck2 from Candida albicans in complex with inhibitor 2a: 2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine-6-carbonitrile; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.03 Å)