9E39

Gag CA-SP1 (T8I) immature lattice bound with Bevirimat from enveloped virus like particles

Summary for 9E39

• Entry DOI: 10.2210/pdb9e39/pdb
• EMDB information: 47475
• Descriptor: Gag, 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid, INOSITOL HEXAKISPHOSPHATE, ... (4 entities in total)
• Functional Keywords: hiv-1, gag, ca-sp1, inhibitor, virion assembly, viral protein
• Biological source: Human immunodeficiency virus type 1 (HBX2 ISOLATE) (HIV-1)
• Total number of polymer chains: 18
• Total formula weight: 460248.03

Authors

Wu, C.,Meuser, M.E.,Xiong, Y. (deposition date: 2024-10-23, release date: 2025-10-29)

• Primary citation: Wu, C.,Meuser, M.E.,Rey, J.S.,Meshkin, H.,Yang, R.,Devarkar, S.C.,Freniere, C.,Shi, J.,Aiken, C.,Perilla, J.R.,Xiong, Y.; Structural insights into inhibitor mechanisms on immature HIV-1 Gag lattice revealed by high-resolution in situ single-particle cryo-EM; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.71 Å)