9DHM

Crystal structure of PIsnA complexed with an isonitrile product

Summary for 9DHM

• Entry DOI: 10.2210/pdb9dhm/pdb
• Related: 9DH1 9DH4
• Descriptor: L-tyrosine/L-tryptophan isonitrile synthase family protein, PHOSPHATE ION, (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoic acid (3 entities in total)
• Functional Keywords: isonitrile group, aromatic amino acid, ribose-5-phosphate, transferase
• Biological source: Photorhabdus luminescens
• Total number of polymer chains: 2
• Total formula weight: 72563.87

Authors

Kim, W.,Zhang, Y.J.,Guo, M. (deposition date: 2024-09-04, release date: 2025-07-16)

• Primary citation: Chen, T.Y.,Kim, W.,Guo, M.,Yao, A.,Zhang, Y.J.,Chang, W.C.; Studies of Isonitrile Synthases Help Elucidate the Mechanism of Isonitrile Installation; Acs Catalysis, :12005-12013, 2025; DOI: 10.1021/acscatal.5c03282

Experimental method

X-RAY DIFFRACTION (3.21 Å)