9DCZ

Designed allosteric facilitated dissociation switch AS1 in complex state TH with methylated lysines, crystal #1

Summary for 9DCZ

• Entry DOI: 10.2210/pdb9dcz/pdb
• Descriptor: Designed allosteric facilitated dissociation switch AS1 H, Designed allosteric facilitated dissociation switch AS1 T, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: de novo protein, design model, effector, kinetics and dynamics, protein-protein interactions
• Biological source: synthetic construct; More
• Total number of polymer chains: 4
• Total formula weight: 88222.89

Authors

Bera, A.K.,Broerman, A.,Baker, D. (deposition date: 2024-08-27, release date: 2025-08-20)

• Primary citation: Broerman, P.,Bera, A.K.,Baker, D.; Design of facilitated dissociation enables temporal control over cytokine signaling; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)