9DB3

Molecular basis of pathogenicity of the recently emerged FCoV-23 coronavirus. FCoV-23 S long with Do in swung-out conformation

This is a non-PDB format compatible entry.

Summary for 9DB3

• Entry DOI: 10.2210/pdb9db3/pdb
• Related: 9DB0
• EMDB information: 46714
• Descriptor: FCoV-23 S long with Do in swung-out conformation, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: coronavirus, alphacoronavirus, feline coronavirus, cryo-em, neutralization assays, binding assays, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein
• Biological source: Feline coronavirus
• Total number of polymer chains: 3
• Total formula weight: 520332.28

Authors

Tortorici, M.A.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2024-08-23, release date: 2025-07-09)

• Primary citation: Tortorci, M.A.,Choi, A.,Gibson, C.A.,Lee, J.,Brown, J.T.,Stewart, C.,Joshi, A.,Harari, S.,Willoughby, I.,Treichel, C.,Leaf, E.M.,Bloom, J.D.,King, N.P.,Tait-Burkard, C.,Whittaker, G.R.,Veesler, D.; Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics; Nature, 2025; DOI: 10.1038/s41586-025-09155-z

Experimental method

ELECTRON MICROSCOPY (2.3 Å)