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9D8M

Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V fluorophore in the dark state at pH 4

Summary for 9D8M
Entry DOI10.2210/pdb9d8m/pdb
DescriptorRetinol-binding protein 2, (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine, ACETIC ACID, ... (4 entities in total)
Functional Keywordshuman cellular retinol binding protein ii, hcrbpii, retinal binding protein, protein engineering, fluorescent protein, retinol binding protein
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight31848.15
Authors
Ehyaei, N.,Bingham, C.,Geiger, J.H. (deposition date: 2024-08-19, release date: 2025-02-12)
Primary citationBingham, C.,Maity, S.,Ehyaei, N.,Cantrell, J.,Gwasdacus, J.,Sheng, W.,Vasileiou, C.,Borhan, B.,Geiger, J.H.
Photoswitching fluorescence via a novel Trp-flap mechanism
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.201 Å)
Structure validation

237992

数据于2025-06-25公开中

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