9CZN
Type Ic amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Summary for 9CZN
| Entry DOI | 10.2210/pdb9czn/pdb |
| EMDB information | 46422 |
| Descriptor | Amyloid-beta protein 42 (1 entity in total) |
| Functional Keywords | amyloid filaments, cotton wool plaques, neurodegeneration, neuropeptide, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 20 |
| Total formula weight | 71202.56 |
| Authors | Hoq, M.R.,Vago, F.S.,Ozcan, K.A.,Bharath, S.R. (deposition date: 2024-08-05, release date: 2024-10-02) |
| Primary citation | Hoq, M.R.,Fernandez, A.,Vago, F.S.,Hallinan, G.I.,Bharath, S.R.,Li, D.,Ozcan, K.A.,Garringer, H.J.,Jiang, W.,Vidal, R.,Ghetti, B. Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease. Acta Neuropathol, 148:20-20, 2024 Cited by PubMed: 39147931DOI: 10.1007/s00401-024-02786-y PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.6 Å) |
Structure validation
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