9CZ5

Crystal structure (II) of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, CL03049

This is a non-PDB format compatible entry.

Summary for 9CZ5

• Entry DOI: 10.2210/pdb9cz5/pdb
• Descriptor: Farnesyl pyrophosphate synthase, {[(6-{4-[(1R)-2,2-difluorocyclopropyl]phenyl}thieno[2,3-d]pyrimidin-4-yl)amino]methylene}bis(phosphonic acid), GLYCEROL, ... (5 entities in total)
• Functional Keywords: transferase, enzyme-ligand complex, cryptic pocket binder, isoprenoid biosynthesis
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 44765.08

Authors

Pandya, V.R.,Park, J. (deposition date: 2024-08-03, release date: 2025-10-29)

• Primary citation: Pandya, V.R.,Park, J.; Crystal structure (II) of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, CL03049; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.652 Å)