9CZ4

Crystal Structure (I) of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, CL03049

This is a non-PDB format compatible entry.

Summary for 9CZ4

• Entry DOI: 10.2210/pdb9cz4/pdb
• Descriptor: Farnesyl pyrophosphate synthase, SULFATE ION, {[(6-{4-[(1R)-2,2-difluorocyclopropyl]phenyl}thieno[2,3-d]pyrimidin-4-yl)amino]methylene}bis(phosphonic acid), ... (5 entities in total)
• Functional Keywords: transferase, enzyme-ligand complex, cryptic pocket binder, isoprenoid biosynthesis
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 44287.77

Authors

Pandya, V.R.,Park, J. (deposition date: 2024-08-03, release date: 2025-10-29)

• Primary citation: Pandya, V.R.,Park, J.; Crystal Structure (I) of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, CL03049; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)