9CY2

Crystal structure of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, JDS05120

Summary for 9CY2

• Entry DOI: 10.2210/pdb9cy2/pdb
• Descriptor: Farnesyl pyrophosphate synthase, PHOSPHATE ION, [({5-[4-(cyclopropyloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid), ... (4 entities in total)
• Functional Keywords: transferase, enzyme-ligand complex, cryptic pocket binder, isoprenoid biosynthesis
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 43640.21

Authors

Pandya, V.R.,Park, J. (deposition date: 2024-08-01, release date: 2025-10-29)

• Primary citation: Pandya, V.R.,Park, J.; Crystal structure of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, JDS05120; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)