9CY2

Crystal structure of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, JDS05120

9CY2 の概要

• エントリーDOI: 10.2210/pdb9cy2/pdb
• 分子名称: Farnesyl pyrophosphate synthase, PHOSPHATE ION, [({5-[4-(cyclopropyloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid), ... (4 entities in total)
• 機能のキーワード: transferase, enzyme-ligand complex, cryptic pocket binder, isoprenoid biosynthesis
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43640.21

構造登録者

Pandya, V.R.,Park, J. (登録日: 2024-08-01, 公開日: 2025-10-29)

• 主引用文献: Pandya, V.R.,Park, J.; Crystal structure of human farnesyl pyrophosphate synthase in complex with a cryptic pocket ligand, JDS05120; To Be Published,

実験手法

X-RAY DIFFRACTION (2.2 Å)