9CPJ

Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1

Summary for 9CPJ

• Entry DOI: 10.2210/pdb9cpj/pdb
• NMR Information: BMRB: 31191
• Descriptor: RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') (1 entity in total)
• Functional Keywords: cug repeats, rna, myotonic dystrophy type 1, dm1, 5'cug/3'guc
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 8267.00

Authors

Chen, J.L.,Taghavi, A.,Disney, M.D.,Fountain, M.A.,Childs-Disney, J.L. (deposition date: 2024-07-18, release date: 2024-08-07)

• Primary citation: Chen, J.L.,Taghavi, A.,Frank, A.J.,Fountain, M.A.,Choudhary, S.,Roy, S.,Childs-Disney, J.L.,Disney, M.D.; Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1.; Bioorg.Med.Chem.Lett., :129888-129888, 2024; PubMed: 39002937; DOI: 10.1016/j.bmcl.2024.129888

Experimental method

SOLUTION NMR