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9CKS

Human G protein-coupled receptor kinase 5-D311N in complex with ATP and manganese ion

Summary for 9CKS
Entry DOI10.2210/pdb9cks/pdb
DescriptorG protein-coupled receptor kinase 5, PHOSPHATE ION, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywordsgpcr, grk, g protein-coupled receptor, g protein-coupled receptor kinase, gpcr signaling, signaling protein
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight69588.82
Authors
Chen, Y.,Tesmer, J.J.G. (deposition date: 2024-07-09, release date: 2025-07-16)
Primary citationChen, Y.,Tesmer, J.J.G.
Structures of G protein-coupled receptor kinase 5 in multiple conformations reveals mechanism of activation and inhibition
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.08 Å)
Structure validation

239149

数据于2025-07-23公开中

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