9CJ8

Lineage IV Lassa virus glycoprotein (Josiah) in complex with rabbit polyclonal antibody (LAVA01-like epitope)

Summary for 9CJ8

Entry DOI	10.2210/pdb9cj8/pdb
EMDB information	45625
Descriptor	Rabbit polyclonal Fv heavy chain, Rabbit polyclonal Fv light chain, Glycoprotein G1, ... (9 entities in total)
Functional Keywords	lassa, polyclonal antibody, ll-1, glycoprotein, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Lassa virus Josiah More
Total number of polymer chains	8
Total formula weight	250198.80
Authors	Brouwer, P.J.M.,Perrett, H.R.,Ward, A.B. (deposition date: 2024-07-05, release date: 2024-09-25, Last modification date: 2024-10-09)
Primary citation	Brouwer, P.J.M.,Perrett, H.R.,Beaumont, T.,Nijhuis, H.,Kruijer, S.,Burger, J.A.,Bontjer, I.,Lee, W.H.,Ferguson, J.A.,Schauflinger, M.,Muller-Krauter, H.,Sanders, R.W.,Strecker, T.,van Gils, M.J.,Ward, A.B. Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses. Cell Rep, 43:114708-114708, 2024 Cited by PubMed: 39243373 DOI: 10.1016/j.celrep.2024.114708 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.74 Å)

Structure validation